This doesn't really apply in my field (social sciences) but I know a number of more technical fields have made the jump to electronic texts; since science and computer texts often cost well over $100, the ebook is still a significant savings, plus you don't have to lug around a 20 kilo backpack on campus.
There are a number of history and poli sci books that are "classics," huge, and unavailable electronically. None of them are that expensive, but I'd pay nearly the same price for an e-copy just to avoid the mass.
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