I have an H2O and yes, it is compatible with Windows 10. But, there is a bug in Windows 10 Anniversary Edition that doesn't properly read the H2O. The bug is fixed in the Insider release. So the thinking is that this may be fixed sometime in September.
Read the following thread in its entirety as it does have a solution that will work with Windows 10AU.
https://www.mobileread.com/forums/sho...d.php?t=276349