How do you reduce the size and quality of the images? I'd try first going to grayscale (unless the page has colours), and then adjusting the levels (not just the contrast) to have a white background with no texture and black text. Then reduce the pixel size to the minimum you'll be satisfied with, and save as JPG with the highest compression level you are satisfied with. Reducing the number of grey levels to something like 16 before saving could also help.
And do you need to convert it PDF? Can't you just read the CBZ (CBR or CB7 could be somewhat smaller)?
I you post a couple of sample pages I could have a go and give you some specific settings...
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