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You can for an android tablet that has a bootloader that can be unlocked, and has a version of TWRP available. The problem is that unlocking the bootloader will wipe your data. I always unlock the bootloader as soon as I buy a device.
TWRP can create a backup image of your device that includes both the system and data partitions. You can copy the backup to another device for safekeeping or make the backup to your sd card if the device has one.
You can use Titanium Backup to backup your apps and app data if you are rooted.
The best place to get this kind of info is on the XDA developers site.
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