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FWIW: I am in full agreement with BR and Joanna, especially if the research process includes writing as well as reading. I can't imagine writing papers and articles without a real academic citation and bibliography manager. The pain is too great. For example, changing all the citations of a paper to match what the publishing venue required took far more time than I was willing to spend (think ACM vs IEEE vs Springer publishing styles). Having automatic citation generation makes that problem go away.
Another point: research bibliographies require specific information that calibre doesn't deal with very well. For me the largest problem is people and roles, for example authors, editors, translators, organizers, reviewers, and the like. A person can have multiple roles in the same time paper. In some publishing venues, the role controls how the name is to be displayed. A bibliographic data manager can deal with this.
During my 8 years or so as a writing researcher I tried Bibtex, Endnote, Zotero, and a product that no longer exists. BibTeX lost out because I decided not to use LaTeX. Zotero worked quite well but was still in its infancy back then (may be better or worse now). I ended up using Endnote because it worked beautifully, was what my coauthors used, and was supplied by my university.
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