I recently updated my W7HP laptop to W10 (I did the desktop quite a bit ago)
I attached My TAB2, Calibre asked if I wanted to Manage
It appeared to work.... (the job whee spun)
Spoiler:
calibre, version 2.57.1
ERROR: Error: Error communicating with device
Cannot delete object: hr=2150236162 facility=42 error_code=2 description: Shutdown was already called on this object or the object that owns it.
Traceback (most recent call last):
File "site-packages\calibre\gui2\device.py", line 87, in run
File "site-packages\calibre\gui2\device.py", line 504, in _books
File "site-packages\calibre\devices\mtp\driver.py", line 283, in books
File "site-packages\calibre\devices\mtp\driver.py", line 309, in write_metadata_cache
File "site-packages\calibre\devices\mtp\driver.py", line 149, in put_calibre_file
File "site-packages\calibre\devices\mtp\windows\driver.py", line 35, in check_thread
File "site-packages\calibre\devices\mtp\windows\driver.py", line 437, in put_file
File "site-packages\calibre\devices\mtp\windows\driver.py", line 35, in check_thread
File "site-packages\calibre\devices\mtp\windows\driver.py", line 422, in delete_file_or_folder
WPDError: Cannot delete object: hr=2150236162 facility=42 error_code=2 description: Shutdown was already called on this object or the object that owns it.
The TAB went to sleep

(and I do not know how to stop that when connected to USB)
Calibre Companion works