Just use MathML/CSS 3 in epub 2 -- it will work everywhere that MathML works in epub 3. The only exception being the idiotic epubcheck.
The simple fact that the IDPF failed to grasp in their epub 3 process is that *all* future ebook renders are going to be based on browser engines. Which means that they will display whatever a browser can display, regardless of the "version" that you put into the OPF file in an epub.
Fortunately, the IDPF saw the error of their ways for EPUB 3.1
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