There is a plugin for Calibre that will convert to KFX so you can get enhanced typesetting on your Kindle. The problem is that it's hit or miss because it uses a beta of Kindle Previewer to do some of the heavy lifting and that don't work for this all that reliably.
https://www.mobileread.com/forums/sho...d.php?t=272407
If you really want enhanced typesetting all the time, you'll want a Reader that uses RMDSK (ADE) because that doesn't need any specialized format to do the typesetting.