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Just an observation: surface area is much larger on a 10" screen than a 6" or 4.7" screen (assuming these are all more or less the same distance from eye). It is going to produce a lot more light, regardless of pixel density. As such it requires more mitigation (keep screen further away, use Night theme, turn brightness down more etc.).
Unfortunately Blue Shade is unusable, as it eliminates almost all contrast in its quest to eliminate blueness. By contrast, iOS's Night Shift doesn't completely eliminate blue even at 'maximum' color shift, but it is a very helpful mitigation otherwise.
Night theme alone would handle most of blue elimination for reading if the screens were OLED (you get real black, i.e., no light emission or energy consumption from black pixels). But until now, those haven't seen broad application, I assume because of other trade-offs.
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