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The Qt path is not hardcoded anywhere. It is detected from the output of qmake, which should be in your PATH
Those include directories are for the windows driver development kit which is need to compile a windows specific module winutil.pyd
You can always create a simple .bat file that sets up the include directories the way they should be on your system, like the bat file used to setup the visual studio command prompt. Once you do that, any extra directories in setup.py will simply have no effect
You should run
python setup.py build_ext
to create the lzx and other C extensions.
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