The bad news is this is a caused by the OpenSSL library in OS X being out of date. And Apple apparently has no plans to update OpenSSL anymore in their install. Details
here.
The good news is Kovid is going to include a copy of OpenSSL in future versions of Calibre on OS X. He's committed the code for it already, so I expect it will be in next Friday's release.
In the meantime, you can still use the FanFicFare web service for SV fics:
http://fanficfare.appspot.com/