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To explain a bit more. ePUB3 uses a large subset of HTML5 as base and is poorly supported in e-readers (applications on tablets/pc are a bit better). ePUB2 is supported quite well (except funny enough in a lot of applications, where stylesheets are mostly ignored) and those use XHTML1.1, which is more or less an XML version of HTML4.
If you want high compatibility and you do not need the 'fancy' stuff of ePUB3, you are most definitely better off with ePUB2.
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