KOReader works with calibre in a number of ways. The file structure that calibre will place on the device, if you send books from calibre to your device, can be defined in calibre. I will assume that you have that setup as you want it already.
KOReader can search the calibre files, on your device, by Title, Author, series and tags.
There are also Wireless features that allow you to interact with calibre running on your PC, and move files from the calibre library, to your device.
Normally I would suggest that you could try
KOReader on Android, but I am not sure it is working correctly on the Boox devices yet. The Kobo and Kindle versions seem to be working much more consistently than the Android version. There are a lot of differences in the Android devices and the Kobos & Kindles are more predictable.
An install guide. You should use Version 8 of the Kobo Start Menu, if you will be using the stock Kobo software to read books as well.
Luck;
Ken