For what it's worth, I've managed to get any and all ADE versions to run under Wine. It's a bit of a pain in the ass for 3.0 and later since they require the .NET Framework version 3 and/or 4/4.5, but it's definitely possible. All you need to do is use Wine 1.7 (possibly the -staging branch) and follow the Wine AppDB instructions for installing .NET 4 (since that also pulls in 3 thus necessarily also 2). Don't skip the "switch the prefix to Windows XP, install whatever, switch it back to Windows 7, install another whatever" steps, though. They're important.
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