As for audiences:
You should make your books available at each of the major stores (or else experiment with Kindle Unlimited).
I don't see why a closed ecosystem would have anything to do with whether or not it is a bad time to publish.
Is there a bad time to publish?
Maybe there is a bad time to work on promotion...
The reading landscape doesn't, to my knowledge, associate a book's success with the store each particular consumer buys it from. So long as people *can* buy it, they will read it, and discuss it with other people, etc.
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