You can and have always been able to create a book in e.g. MS Word/LibreOffice.
calibre includes a very capable DOCX Input plugin which will automagically convert it to EPUB (or anything else).
Alternatively, see @Toxaris' Word Add-In, which does a number of things to ease transition from DOCX ==> EPUB (and performs the final conversion).
If you like fine-grained control, write in markdown, calibre can convert that -- or use LaTeX or DocBook, then convert it with something like Pandoc.
There is a wealth of tools available.
But since you haven't said what specific features you are looking for, we have no idea what to recommend.
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