I don't like the idea of a blurb giving away what happens a quarter way through the book, unless the book itself start in the middle of the action and then backtracks.
I've gotten a little bored with that plot device anyway--I feel like I've read it too many times recently, usually a prologue that shows the protagonist in some grave danger and then chapter one going back however many days or weeks to when the story really starts.
If you pick up a book in the suspense or thriller category, you certainly know that there's going to be something sinister/unexpected coming, so I don't see much point in opening with that sinister/unexpected event; I'd usually rather get there gradually.
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