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I see no indication there one way or another.
Custom columns haven't changed -- insomuch as they have always bee stored in the database.
custom columns built from other columns -- those store the template once for the entire column, then calculate the value for each row dynamically.
Performing functions on all the metadata columns in order to get the value of a custom column built from other columns is slow.
If you use custom columns built from other columns, then calibre will be slower -- no matter what. Sometimes a lot slower -- it depends how many you have.
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