Laptop? (in title)
Desktop? (in the body)
Is there a Networked folder in this picture? on (now poor) WiFi?
Security software (A/V) can change as frequently as hourly (the normal for free versions is a daily update)
Heat will cause a slow down (Throttling), trying to save you CPU from clogged fins or a failing fan
Dying HD will retry their reads or writes (usually, a Clone onto a new drive will still save the pain of a full re-build. do it NOW). Or the drive is just overcrowded and fragmented)
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