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Thank you itimpi.
The problem now seems to be solved.
I had to fight with Windows to even get it to let me uninstall Calibre, which made me realise that, for some unknown reason, the Windows User Account Control had been switched back on (permission conflicts in the past mean we always keep this switched off).
Switching this off and re-installing in a non-Program Files location seems to have fixed things, and I am now a happy Calibre bunny.
Thank you for your time and assistance.
Moira. x
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