I have mine set to refresh every 50 pages (you can manually set it in the Kobo eReader.conf file as numPartialUpdatePageTurns=50 under the Reading section), and have never noticed font degradation that some refer to. It might be because I use a bolder font because of my crappy eyes, maybe that degradation is more noticeable on thinner fonts. But I'm happy with the 50 page refresh.
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