note: I did not read this thread.
My answer is yes, with one caveat: they have to be properly designed. No more than one button on each side of the device, not likely to accidentally trigger yet not requiring significant amounts of force.
I have found that reading in a "full screen mode" with very little margins is my preferred way of reading, despite initially resisting it, but a lack of physical buttons discourage this efficient method of reading: your hands end up covering some of the text.
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