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I looked at your long equation in FireFox, iBooks, Kobo for iPad/iPhone, and Gitden Readers. I think the problem is that the equation is just too long. It renders OK in FireFox, but not in the other readers. I suggest abbreviating "Cumulative Incidence" to "CI" and "Annual Incidence Proportion" to "AIP". That would shorten the equation and maybe keep it on one line.
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