Might as well remove it, since it is pointless to keep. Why waste the disk space?
Will it cause horrible things to happen? No -- but you *might* get confused about which bitness you started. If 64-bit calibre consistently crashes, there is no point wasting time trying it accidentally.
Some people do keep 32-bit and 64-bit calibre installed. The usual reason is so they can test two different versions of calibre. For instance, a plugin developer might want to keep a copy of calibre 1.48 to make sure things keep working on legacy WinXP computers.
No harm is caused.
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