The problem with not specifying justification is that on the Amazon store, such a book will have a ragged right Look Inside preview, while the downloaded book will be justified.
I went through last week's e-book best-seller lists in the Wall Street Journal and found three instances (out of twenty) where this was the case. (All twenty books were justified. To me, that's sufficient reason to specify justified alignment.)
In the past year or two I have read two ragged-right books from major publishers, one being a Daniel Silva thriller and the other being David Mamet's rant about The Secret Knowledge. Neither irritated me sufficiently to return the book (I only paid for the Mamet; the other came from the library) but I was conscious all the time that I was reading what, to me, seemed an amateurish production. Perhaps that's because I've been reading justified books for more than seventy years, and I expect e-books to be as professionally done.
By contrast, the occasional short line (more typical in Kindle editions than widely spaced words) doesn't bother me at all.
(And yes, I often read books on my iPhone 4 held horizontally.)
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