Hi trichobezoar, I am sorry that you are stressed over your niece. It sounds serious, my advice would be to call a suicide hotline in your area, and explain your niece's behavior to them. Then they can tell you what do to do get immediate help for her. Usually a call to a hospital that can observe your niece and evaluate her there. Then they may prescribe anti depressant medication, and recommend her seeking a local AA meeting as soon as she is able. Getting help is the first step and it may prevent a suicide.
I also commend your seeking a spiritual path to get through your stress with your niece. I hope everything turns for the better soon for you & your niece.