[Ken Maltby]

If you mean interactions like completing forms or other extensive text entry, ereaders without keyboards (like the Kobos) are not really adapted to such work. While Koreader is a much better PDF reader than the stock readers, it has to leave off some of the bells and whistles, that Adobe includes in the format.

Of course if you update the sheet(s) offline, say by pencil and then on your PC, you could read the sheets on your ereader. You could use Annotation or Koreader's Evernote plug-in, perhaps.

Luck;
Ken