Never used it, but there is a plugin for calibre to import lists:
https://www.mobileread.com/forums/sho...d.php?t=187831
You will need to convert the word file to a csv list. Depending on how the word file is structered, this can be very easy (if it is done as a table) or difficult.
You could then run calibres fetch metadata option to get the missing data and isbns. As eschwartz has said, you could then sync your library with goodreads also.
For the eBooks it would be a good idea to import the books directly into calibre.
Hope this helps you to get started!