The iRex iLiad and (new) DR1000S can run 3rd party Linux apps (typically lightweight GTK+ based apps are best). The OpenInkPot alternative firmware for the Hanlin (and other devices), opens up the possibility of 3rd party apps, but the lack of a pointing input device makes porting existing apps harder. It is possible to add applications to the Sony's, but I don't know what is required to do so.
Currently EInk is 4, 8, or 16 level grey scale only. However, if you search the forums for color in the thread title you will find several examples of color EInk prototypes.
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