LibrarianSync will only work on JB'ed Kindles.
But calibre will let you normalize metadata and update the ebook files. One incredibly useful tool is plugboards, which allow you to use templates to update metadata fields e.g. adding the calibre series info to the title.
It won't help you make collections faster, but it does allow you to do useful stuff like for instance sort by title and have the prepended series info group like books with like.