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I can't imagine uploading a doc file (however generated) to Createspace. Print editions should have a professional appearance. No automagical conversion is going to achieve that.
I finish my books in Word, then fork them into separate paths: to html and Sigil for the e-book, to Open Office Writer for the print edition. (I find OOW much better than Word for doing the actual layout--headers & footers, hyphenation, drop-caps, widows & orphans--and much, much better in creating the PDF. As Exalted says, PDF is the gold standard for print editions, just as epub is for digital. (All IMHO, of course!)
Sure, this means you must maintain two distinct books, but as a practical matter you'll be doing that anyway, since e-books are so easy to modify and update, and print editions so time consuming.
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