I haven't had the HD since mid-September, but I remember seeing something like your patches of grey, usually late at night after reading for hours in dim ambient lighting, and wondering whether it was my eyes, the book or the reader. I usually decided it was time to let everybody and everything rest, and go to sleep. This was leading to my HD dying on me, but I felt this last was caused by lots of manipulating a problem epub.
Who knows?
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