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I know - it's an old topic and I'm probably way off base in what you're looking for - but I've read a number of fiction books based on some type of apoctalyptic plague / end of the world type books - all of these are from my fictionwise account:
The Road - Cormac Mccarthy - I don't know that it's a plague that wiped everything out though
Plague Year - Jeff Carlson - nanotech plague
Oryx and Crake - Margaret Atwood - I didn't personally like it - but it got really good reviews
Cell - Stephen King - ok it's stretch of the idea of a plague :-)
The Patron Saint of Plagues - Barth Anderson
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