Depending on how old the e-book file is, part of the quality issue (at least for Amazon-supplied titles) may be that up until fairly recently, the Mobi format had a strict limit for image filesize (eventually boosted from 64 to 128 kb as of KindleGen build 1.1 a couple of years ago) and would downgrade anything larger than that during the conversion.
Nowadays, the Kindle Publishing Guidelines say you can have up to 5 mb for an individual image (the section on GIFs still mentions a 127 kb limit, so I don't know if they didn't update this portion, or the 5 mb allowance is for JPEG/PNG only), but anything from before then was likely supplied to Amazon using the older tools which automatically made low-res versions regardless of what the publisher originally put in.
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