wwaldo - Some folks install calibre portable to Dropbox so that they can access it and all its settings and libraries from any windows machine - home computer, laptop, desktop at work, public PC in library etc. Other folks install calibre on a thumb drive and carry it in their pocket/purse.
You have to maintain the library from a windows, os/x or linux platform (preferably only one of them). Calibre doesn't take that much space ~200MB for 64bit, ~30MB for config data and say 2.5GB for a reasonable size library - so 3GB is maybe all you'll save.
Unless you have a lot of large 'books' eg I have one library that's 600GB, but its full of video, audio and image albums.
BR
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