Just personal opinions ... I would only make use of a Settings backup (not books/database) and I would only use it to set up a new (or factory reset) device. I've already got slightly different settings for my phone and tablet but cloning backed up settings from the most similar device would do most of the work.
Having said that, when I last set up a new device it wasn't very onerous to have the old and new side by side and work through the settings one by one. Setting up the format folders took the longest but a backup wouldn't have helped, because the new device was KitKat and the old one wasn't, so I would have had to set them manually anyway.
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