I think most of us would agree that a large-screen tablet is the ideal PDF reader. eInk devices are designed primarily for long battery life and, in comparison to tablets, have a slow CPU and very limited memory. This makes them a poor choice for rendering PDF files, which often requires a great deal of processing power and memory.
I read a great many academic PDFs and, for me personally, the ideal combination is an iPad with the "Goodreader" app, but there are many excellent Android tablets out there too.
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