@Kythe42 - I suggest you copy it to somewhere like C:\_Temporary\calibre and set the CALIBRE_CONFIG_DIRECTORY to point to that location. If that fixes the problem then move it somewhere sensible. I have mine in the same location as my libraries E:\Calibre Libraries, which also means it gets backed up with the libraries.
Another thing you could try is to exclude the %APPDATA%\calibre from your AV scanning, maybe an AV update has started to mess around with permissions Ψ²
BR
Last edited by BetterRed; 06-01-2014 at 06:11 PM.
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