I have chronic severe migraines and I use two lit e-ink screens other than Kobo ones and I have no problem with them contributing to my headaches. Lit e-ink is OK for me anyway. Can't speak for Kobo.
I use the light pretty low, particularly in a dark room. I don't like the contrast of a light screen in a dark room so I keep it as low as I comfortably can, or that contrast does seem to bother me.
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