Honestly, I'd suggest you take a long hard second (third, fourth) look at a tablet. PDF handling is vastly superior, and their glass screens are also sturdier than e-ink. If you manage the brightness/colours appropriately, eyestrain is likely to be minimal.
Dealbreakers might include a lot of time reading in direct bright sunlight, or a need for weeks of battery life without access to power. If those aren't present, really, think again.
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