@Kovid, I'm not convinced.
The default temp folder is shared by many applications, browsers, photo editors, Lightroom, Breeze, Sigil, Acrobat etc. I've not noticed any similar problems in the forums for those applications or in the major Windows 7 forums.
I use a photo library package that has similarities to calibre, MySql database for metadata, metadata embedded in images, metadata sidecar files, folder creation, rename, move etc. It writes lots of folders and files to the Temp folder for searches, edits, resizes etc. It's not as 'good' as calibre is at removing things from Temp - i.e stuff is left lying around, but Disk Cleanup takes care of that. It is Windows only, it doesn't spawn worker processes, although it is it is multi-threaded. Its a bespoke program written in C++.
I fixed a friends PC recently, it had MSE, McAfee, and NOD32 installed and running! The machine ran like a dog, e.g. 20 minutes to shut down - none of the three excluded anything except some System/Hidden folders like System Volume Information.
According to the owner calibre wasn't as significantly effected performance-wise as were some other programs, like browsers and Lightroom. Before I removed the unwanted Security Suites (McAfee & NOD32) I ran calibre, did a couple of conversions, used the reader and downloaded some metadata - no problems, calibre was sluggish but nowhere near as bad as firefox and Lightroom.
BR
The extra security suites were installed by a someone from ANU Admin!
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