Why did you resurrect a 3-year-old thread for this? You should have started a new thread.
Try converting .doc to filtered HTML, and see if that preserves the italics. Normally converting a .doc to mobipocket will retain the italics. Don't know why your doc is different. If it doesn't preserve them, you can then edit the HTML to re-add the italics, then convert that to .mobi.
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