I think you will find it is the opposite. The font size specified in the reader settings is in points. The range is from 12 to 58. But, the code in the books specifies relative sizes. It is common to find the fonts size in the books specified as "small" or "normal" or as a percentage or some other relative size. It is also common to find absolute sizes in the books. As far as I know these will be used without change.
The only thing you can do is fix the books. If the formatting isn't to my liking, I usually edit them and fix the font sizes used and a few other things I don't like.
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