I've found when you subest the fonts, you do reduce the size of the eBook to a more manageable size, So convert the ePub with the emebdded fonts with subsetting to AZW3 and it might be OK, But the one thing to note with the Kindle is that chances are that the line height is going to be large and ugly looking and there's not a lot you can do to fix this other then use a font that's had the metrics modified.
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