The slowness you describe is not normal and likely has nothing to do with calibre itself. It's caused by something in the software environment on your machine, unfortunately there's no easy way to determine what that may be.
General tips, that may or may not help:
1) Defragment your hard disk
2) Disable your antivirus
3) Try to eliminate as many programs running int he background as possible
4) Run a registry cleaner
5) Update the drivers on your computer
If nothing works, you are left with the old panacea of re-installing windows.
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