AFAIK it has nothing to do with the bold/italic bug, but it is influenced by font type and font size: Changing one of these can make the bug disappear for the page you're on, but that doesn't mean it won't be back a few pages later.
Why don't you use metazoa's patch to get rid of the bug? Although that might not work for kepubs. I only use epubs, and for them it works like a charm.
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