I am receiving the same problem upon updating calibre and installing the Marvin XD plugin (I already had the OS Reader Application plugin installed).
The only difference for me is that I had updated calibre to v1.30.
The error message I received is as follows:
calibre, version 1.3.0
ERROR: Startup error: There was an error during calibre startup. Parts of calibre may not function. Click Show details to learn more.
Traceback (most recent call last):
File "site-packages/calibre/gui2/main.py", line 234, in initialize_db_stage2
File "site-packages/calibre/gui2/main.py", line 183, in start_gui
File "site-packages/calibre/gui2/ui.py", line 204, in initialize
File "site-packages/calibre/gui2/actions/__init__.py", line 142, in do_genesis
File "calibre_plugins.marvin_manager.action", line 126, in genesis
File "calibre_plugins.marvin_manager.action", line 257, in init_options
File "calibre_plugins.marvin_manager.annotations_db ", line 303, in connect
OperationalError: unable to open database file
I look forward to a solution for this problem.