An interesting cross-section of views. Thanks everyone. If additional punctuation is not actually needed then I agree that it is better left out.
Apk, "now" was intended to be against the second clause, as in: until recently he did know where Bill was, but now he doesn't.
I can see the awkwardness referred to, but I had thought the meaning was fairly clear. The intention was to give the sense of a man feeling self-pity without actually saying that, the idea being that "who knows where" is a sort of defeated and helpless way of describing the separation.
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