Why would you do this, if you have calibre? There you can use tags, which are superior to any folder structure. If you use folders, you have to put books under one and only one label. And if you - some time in the future - wish to change it, it will be very difficult.
You are free to use as few or as many tags as you like. So you can go for the system you have in mind, but you would also be able to make something like a subject catalog.
You could also use custom columns, so you use one column for something like the Dewey System and another one for more private tags and another one for subjects.
Folders are very simplistic. Calibre is more of a database, with the added comfort to be tailored to books.
And if you need it on devices where calibre doesn't work, you can make catalogues.
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