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You might want to have a look at Mendeley and Citavi - there's a Calibre plugin that imports tags from Mendeley - at least I think that's what it does.
Citavi is quite good but for me the Free version is too restrictive and the Pay4Me version is not worth the money; not because its a bad product - but because I have a very small software budget.
Do a search for both in Mobileread and you should find some threads that discuss them.
PDF's have limited embedded metadata capabilities, and from memory Calibre wont extract much from them anyway. But getting academia, consultancies and institutions to populate their publications with meaningful content is an even bigger uphill battle.
As I understand it to download the metadata as Calibre does from Amazon, GoodReads etc requires the 'publisher' put a documented API library into the public domain and that a publicly accessible metadata repository be made available and that be updated and maintained accurately.
BR
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